Download immune 3'aQTLs by cell type:

Guide

1. Download page provides the immune 3'aQTLs with FDR value < 0.05 across 18 human immune baseline cell types and 8 stimulation conditions.

Immune cell type Study Sample Size File Name
Naive B cells DICE 88  B_NAIVE.cis_3aQTL_FDR0.05.txt.gz 
Naive CD4+ T cells DICE 85  CD4_NAIVE.cis_3aQTL_FDR0.05.txt.gz 
Naive CD8+ T cells DICE 86  CD8_NAIVE.cis_3aQTL_FDR0.05.txt.gz 
CD4+ T-cells BLUEPRINT 162  CD4T-cells.cis_3aQTL_FDR0.05.txt.gz 
Activated CD4+ cells DICE 86  CD4_N_STIM.cis_3aQTL_FDR0.05.txt.gz 
Activated CD8+ cells DICE 85  CD8_N_STIM.cis_3aQTL_FDR0.05.txt.gz 
Monocytes BLUEPRINT 191  Monocytes.cis_3aQTL_FDR0.05.txt.gz 
Classical Monocytes DICE 88  CLASSICAL_MONOCYTES.cis_3aQTL_FDR0.05.txt.gz 
Non-classical Monocytes DICE 87  NONCLASSICAL_MONOCYTES.cis_3aQTL_FDR0.05.txt.gz 
NS EvoImmunoPop 195  NS.cis_3aQTL_FDR0.05.txt.gz 
NK cells DICE 87  NK_CD16POS.cis_3aQTL_FDR0.05.txt.gz 
Neutrophils BLUEPRINT 187  Neutrophils.cis_3aQTL_FDR0.05.txt.gz 
Naive Treg cells DICE 86  TREG_NAIVE.cis_3aQTL_FDR0.05.txt.gz 
Memory Treg cells DICE 86  TREG_MEMORY.cis_3aQTL_FDR0.05.txt.gz 
TFH cells DICE 86  TFH.cis_3aQTL_FDR0.05.txt.gz 
TH1/17 cells DICE 85  TH1-17.cis_3aQTL_FDR0.05.txt.gz 
TH17 cells DICE 86  TH17.cis_3aQTL_FDR0.05.txt.gz 
TH1 cells DICE 79  TH1.cis_3aQTL_FDR0.05.txt.gz 
TH2 cells DICE 86  TH2.cis_3aQTL_FDR0.05.txt.gz 
LPS EvoImmunoPop 180  LPS.cis_3aQTL_FDR0.05.txt.gz 
PAM3CSK4 EvoImmunoPop 190  PAM3CSK4.cis_3aQTL_FDR0.05.txt.gz 
R848 EvoImmunoPop 187  R848.cis_3aQTL_FDR0.05.txt.gz 
Dendritic cells Immvar 95  immvar_basename.cis_3aQTL_FDR0.05.txt.gz 
FLU Immvar 244  immvar_FLU.cis_3aQTL_FDR0.05.txt.gz 
IFNB1 Immvar 220  immvar_IFNB.cis_3aQTL_FDR0.05.txt.gz 
IAV EvoImmunoPop 195  IAV.cis_3aQTL_FDR0.05.txt.gz 

2. Download page provides all the immune 3'aQTLs across 18 human immune baseline cell types and 8 stimulation conditions.

Immune cell type Study Sample Size File Name
Naive B cells DICE 88  B_NAIVE.cis_3aQTL_all.txt.gz 
Naive CD4+ T cells DICE 85  CD4_NAIVE.cis_3aQTL_all.txt.gz 
Naive CD8+ T cells DICE 86  CD8_NAIVE.cis_3aQTL_all.txt.gz 
CD4+ T-cells BLUEPRINT 162  CD4T-cells.cis_3aQTL_all.txt.gz 
Activated CD4+ cells DICE 86  CD4_N_STIM.cis_3aQTL_all.txt.gz 
Activated CD8+ cells DICE 85  CD8_N_STIM.cis_3aQTL_all.txt.gz 
Monocytes BLUEPRINT 191  Monocytes.cis_3aQTL_all.txt.gz 
Classical Monocytes DICE 88  CLASSICAL_MONOCYTES.cis_3aQTL_all.txt.gz 
Non-classical Monocytes DICE 87  NONCLASSICAL_MONOCYTES.cis_3aQTL_all.txt.gz 
NS EvoImmunoPop 195  NS.cis_3aQTL_all.txt.gz 
NK cells DICE 87  NK_CD16POS.cis_3aQTL_all.txt.gz 
Neutrophils BLUEPRINT 187  Neutrophils.cis_3aQTL_all.txt.gz 
Naive Treg cells DICE 86  TREG_NAIVE.cis_3aQTL_all.txt.gz 
Memory Treg cells DICE 86  TREG_MEMORY.cis_3aQTL_all.txt.gz 
TFH cells DICE 86  TFH.cis_3aQTL_all.txt.gz 
TH1/17 cells DICE 85  TH1-17.cis_3aQTL_all.txt.gz 
TH17 cells DICE 86  TH17.cis_3aQTL_all.txt.gz 
TH1 cells DICE 79  TH1.cis_3aQTL_all.txt.gz 
TH2 cells DICE 86  TH2.cis_3aQTL_all.txt.gz 
LPS EvoImmunoPop 180  LPS.cis_3aQTL_all.txt.gz 
PAM3CSK4 EvoImmunoPop 190  PAM3CSK4.cis_3aQTL_all.txt.gz 
R848 EvoImmunoPop 187  R848.cis_3aQTL_all.txt.gz 
Dendritic cells Immvar 95  immvar_basename.cis_3aQTL_all.txt.gz 
FLU Immvar 244  immvar_FLU.cis_3aQTL_all.txt.gz 
IFNB1 Immvar 220  immvar_IFNB.cis_3aQTL_all.txt.gz 
IAV EvoImmunoPop 195  IAV.cis_3aQTL_all.txt.gz 

3. Download page provides data for generating the figures in the manuscript.

Figure File Name
Fig.1b  See Table S1 
Fig.1c  lncRNA_CDS_for_R_20230209.txt.gz 
Fig.1d  gcta_output_file.txt.gz 
Fig.1e  Fig.1e.immune.eQTL.txt.gz 
Fig.1f  Fig.1f.immune.3aQTL.txt.gz 
Fig.1g  R2_eqtl_3aqtl.txt.gz 
Fig.2a-2c  Fig.2c_cell_type_specific_full.txt.gz   FastQTLSumStats.mash.rds 
Fig.2d  fig2d.xlsx 
Fig.2e  fig2e.xlsx 
Fig.2f  genebody_QTL_enrichment_heatmap.txt.gz 
Fig.3  B_NAIVE_PDUI.txt.gz   CD4_NAIVE_PDUI.txt.gz   CD4_N_STIM_PDUI.txt.gz   CD4T-cells_combined_All_PDUIs.txt.gz   CD8_NAIVE_PDUI.txt.gz   CD8_N_STIM_PDUI.txt.gz   CLASSICAL_MONOCYTES_PDUI.txt.gz   IAV_AFB_PDUIs.txt.gz   IAV_CEU_PDUIs.txt.gz   immvar_basename_combined_PDUIs.txt.gz   immvar_FLU_combined_PDUIs.txt.gz   immvar_IFNB_combined_PDUIs.txt.gz   LPS_AFB_PDUIs.txt.gz   LPS_CEU_PDUIs.txt.gz   Monocytes_combined_All_PDUIs.txt.gz   Neutrophils_combined_All_PDUIs.txt.gz   NK_CD16POS_PDUI.txt.gz   NONCLASSICAL_MONOCYTES_PDUI.txt.gz   NS_AFB_PDUIs.txt.gz   NS_CEU_PDUIs.txt.gz   PAM3CSK4_AFB_PDUIs.txt.gz   PAM3CSK4_CEU_PDUIs.txt.gz   R848_AFB_PDUIs.txt.gz   R848_CEU_PDUIs.txt.gz   TFH_PDUI.txt.gz   TH1-17_PDUI.txt.gz   TH17_PDUI.txt.gz   TH1_PDUI.txt.gz   TH2_PDUI.txt.gz   TREG_MEMORY_PDUI.txt.gz   TREG_NAIVE_PDUI.txt.gz 
Fig.4a  Fig4a_EvoImmunoPop_specific.txt.gz 
Fig.4b  See Table S4 
Fig.4e  See Table S6 
Fig.5a-5d  See Table S8 
Fig.5e  Fig.5e.enrichment_summary.all.txt.gz 
Fig.6  See Table S9