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Precision medicine
Shenzhen Bay Laboratory
Computational and Disease Genomics Lab
Our lab is focused on developing and applying robust bioinformatics methods to large-scale, high-throughput, multi-dimensional Genomics, Epigenomics, and Transcriptomics data with the main emphasis on elucidating and understanding human disease progression and development, which is further expected to translate to public health practice.
Recent News
August 23th, 2024
New Grant
Congratulations to Dr. Ruofan Ding in our team for receiving the Young Scientists Grant of the National Natural Science Foundation of China. This grant will support him to develop computational method for single cell sequencing data.
August 16th, 2024
2024 ASHG Trainee Research Excellence Award
Congratulations to our student Hui, who has received the Prestigious 2024 predoctoral Trainee Research Excellence Award. Also, Xudong has received the Reviewers’ Choice Award as his abstract ranked within the top 10% of all abstracts. Cheers!
July 31st, 2024
2024 ASHG Annual Meeting Oral Talk
Hui’s abstract has been ACCEPTED as a oral presentation at the ASHG 2024 Annual Meeting. There are less than 10% of abstracts can be selected as oral presentations. Cheers!
June 18th, 2024
New Paper (Sci. Adv.)
Our cancer alternative tandem TSS paper has finally been accepted by Science Advances. We have developed a new computational method (DATTSS) and demonstrated the widespread dysregulation of tandem TSS usage in tumors. Our findings suggest dysregulated tandem TSS usage represents an additional layer of cancer-associated transcriptome alterations.
February 13th, 2024
New Paper (Nat. Commun.)
Our cancer susceptibility genes paper has finally been accepted by Nature Communications. We have demonstrated a distinct class of cancer susceptibility genes revealed by alternative polyadenylation transcriptome-wide association study. Congratulations to Hui and Zeyang.
January 26th, 2024
Award
Congratulations to our student Qixuan for being awarded the Shenzhen Bay Laboratory (SZBL) Director's Scholarship by Prof. Nieng Yan, Director of the SZBL.