Shenzhen Bay Laboratory
Computational and Disease Genomics Lab
Our lab provides a supportive environment that strives to help students achieve their full potential as both scientists and individuals.
Principal Investigator
Lei Li（李磊）, PhD
Lei Li received his bioinformatics training in The CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences and later obtained his PhD from the Chinese University of Hong Kong in Hong Kong in 2013. He received Postdoc trainings in the lab of Jörg Vogel at the University of Würzburg in Germany between 2013-2016, and in the lab of Wei Li at the Baylor College of Medicine, University of California Irvine in USA between 2016-2021. From February of 2021, he is a Principal Investigator at the Shenzhen Bay Laboratory, China.
Dr. Li is a recipient of National Natural Science Fund for Excellent Young Scientists (Oversea), and Oversea High-Caliber Personnel Award (Level B), ShenZhen.
Phone: (0755) 2684 9284
Email: lei.li#szbl.ac.cn
Assistant Researcher
Xudong Zou, PhD
Xudong Zou received his Ph.D. in Bioinformatics from Peking University in 2018. He received Postdoc training in the lab of Wei Chen at the Southern University of Science and Technology between 2018-2020. His research currently focuses on the functional interpretation of human non-coding variants, especially the transcription and post-transcription (alternative splicing and polyadenylation) regulation of molecular mechanisms responsible for disease/traits.
Email: zouxd#szbl.ac.cn
ORCID
Wenyan Chen, PhD
Wenyan Chen received her Ph.D. in Bioinformatics from the University of Chinese Academy of Sciences in 2021. She received Postdoc training in Computational and Disease Genomics Lab at Shenzhen Bay Laboratory between 2021-2023. Her research currently focuses on the analysis of the genetic architecture related to human complex traits and diseases in non-coding regions using whole genome, transcriptomes and epigenomes data.
Email: chenwy#szbl.ac.cn
ORCIDPostdoc Fellow
Yangmei Qin, PhD
Yangmei Qin received her Ph.D. in Bioinformatics from Xiamen University in 2019，and has rich experience in high-throughput omics data analysis. Her research currently focuses on the multi-omics analysis and clinical big data mining.
ORCID
Ruofan Ding, PhD
RuoFan Ding received his Ph.D. in Bioinformatics from Xiamen University in 2021, and has experience in multi-omics integration analysis. His research currently focuses on spatial transcriptome and functional rare genetic variation.
ORCID
Ting Zhang, PhD
Ting Zhang received his Ph.D. in Bioinformatics from Northwest A&F University in 2022 and has experience in data mining and platform construction. His research currently focuses on single-cell method development.
ORCID
Zeyang Wang, PhD
Zeyang Wang reveived his Ph.D. in Molecular Biology from University of Munich, Germany in 2020 and has experience in molecular experiments. His research currently focuses on functional characterization of the regulatory activities of non-coding elements.
ORCID
Xixian Ma, PhD
Xixian Ma received his Ph.D. in Computational Biology in Dr. Shuhua Xu's Lab from the University of Chinese Academy of Sciences in 2020. His research currently focuses on the analysis of the genetic architecture related to human complex traits using whole genome, transcriptomes and epigenomes data.
ORCIDResearch Assistant
Yong Zhang
Yong Zhang received His MS in Dr. Jue Ruan's Lab from AGIS Institute at Chinese Academy of Agricultural Sciences in 2022. His interest is focused on bioinformatics method development.
ORCID
Shuxin Chen
Shuxin Chen received her MS in Zhejiang A&F University in 2023. Her research interest is CRISPRi screening and Perturb-seq for functional characterization of SNPs.
ORCID
Xing Li
Xing Li received her MS in NingBo University in 2024. Her research interest is focused on calling somatic variants in single-cell sequencing data.
ORCIDAdministrative Assistant
Xiangli Liu
Phone: (0755) 2684 9253
Email: liuxl#szbl.ac.cn
Xiangli Liu received her MS in Dalian Polytechnic University in 2020, she is an assistant in the administrative work of laboratory.
ORCIDStudents
Hui Chen
Hui Chen received her MS in South China University of Technology in 2021, she is currently a PhD candidate in the lab. Her research currently focuses on integrative analysis of high-throughput multi-omics data for complex diseases based on next-generation sequencing.
ORCID
Kewei Xiong
Kewei Xiong received his BS in Central China Normal University. He is currently a PhD candidate in the lab. His interest is focused on single cell algorithm development.
ORCID
Dinglin Luo
Dinglin Luo is a master's student at Northwest A&F University. Her current research focuses on big data related to complex human diseases.
ORCIDVisiting Students
Shifei Zhang
Shifei Zhang is a master student in Northwest A&F University, major in Bioinformatics. His current research primarily focuses on the functional interpretation of non-coding genetic variants associated with human diseases.
ORCID
Yinuo Wang
Yinuo Wang is the master student in Northwest A&F University. Her research currently focuses on the association of new transcripts on population scale with complex human diseases.
ORCIDAlumni
Liucheng Shi
Visiting Student: 03/2021 ~ 06/2021; Next Position: Student at Columbia University
Wenhao Gou
Visiting Student: 03/2021 ~ 06/2021; Next Position: Student at Columbia University
Zhaozhao Zhao
Visiting Student: 10/2022 ~ 12/2022; Next Position: Postdoc Fellow at Fudan University
Huihui Yang
Visiting Student: 02/2023 ~ 08/2023; Next Position: Student at Central South University
Ziyue Zhang
Visiting Student: 09/2023 ~ 12/2023; Next Position: Student at The Chinese University of Hong Kong, Shenzhen
Xuelian Ma, PhD
Postdoc Fellow: 08/2021 ~ 03/2024; Next Position: Assistant Researcher, Sun Yat-sen University