Welcome to Immune 3'aQTL Atlas!

This resource provides 3' untranslated region (3'UTR) alternative polyadenylation (APA) quantitative trait loci (3'aQTLs) across in 18 human immune baseline cell types and 8 stimulation conditions. Data underlying this project were generated from the DICE project, BLUEPRINT, ImmVar project (available through NCBI Gene Expression Omnibus (GEO) accession number GSE92904) and EvoImmunoPop project (available through European Genome-phenome Archive (EGA) under accession code EGA: EGAS00001001895).



If you use the immune 3′aQTLs in this wetsite, please cite the following papers:

Immune-response 3′UTR alternative polyadenylation quantitative trait loci contribute to variation in human complex traits and diseases

Lei Li1,5*, Xuelian Ma1,5, Ya Cui2,5, Maxime Rotival3, Wenyan Chen1, Xudong Zou1, Ruofan Ding1, Yangmei Qin1, Qixuan Wang1, Lluis Quintana-Murci 3,4, and Wei Li2* (Nature Communications, 2023).

An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability

Lei Li# 1, Kai-Lieh Huang# 2, ..., Eric J. Wagner2,*, and Wei Li1,* (Nature Genetics, 2021).


If you have any further questions or comments, please don't hesitate to contact us.

Lei Li (Lab website):
Institute of Systems and Physical Biology ,Shenzhen Bay Laboratory, China.

Wei Li (Lab website):
Department of Biological Chemistry, School of Medicine, University of California Irvine, California, USA